What is a Log Reduction?

"Log reduction" is a mathematical term used to show the relative number of cells, germs, microbes, etc., reduced in or on something. When the term log reduction is used in CML, it refers to the reduction one's CML, or specifically BCR-ABL. 

For example, a "5-log reduction" means the number of Philadelphia Chromosome positive cells have been reduced 100,000-fold.

Log Reductions

1 log reduction means the number of CML cells is 10 times smaller

2 log reduction means the number of CML cells is 100 times smaller

3 log reduction means the number of CML cells is 1000 times smaller

4 log reduction means the number of CML cells is 10,000 times smaller

5 log reduction means the number of CML cells is 100,000 times smaller